Health and Medicine

FSI’s researchers assess health and medicine through the lenses of economics, nutrition and politics. They’re studying and influencing public health policies of local and national governments and the roles that corporations and nongovernmental organizations play in providing health care around the world. Scholars look at how governance affects citizens’ health, how children’s health care access affects the aging process and how to improve children’s health in Guatemala and rural China. They want to know what it will take for people to cook more safely and breathe more easily in developing countries.

FSI professors investigate how lifestyles affect health. What good does gardening do for older Americans? What are the benefits of eating organic food or growing genetically modified rice in China? They study cost-effectiveness by examining programs like those aimed at preventing the spread of tuberculosis in Russian prisons. Policies that impact obesity and undernutrition are examined; as are the public health implications of limiting salt in processed foods and the role of smoking among men who work in Chinese factories. FSI health research looks at sweeping domestic policies like the Affordable Care Act and the role of foreign aid in affecting the price of HIV drugs in Africa.

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The combination of COVID-19 and global uncertainties — from wars, cost-of-living crises, high cross-national public debts, and impending global recession — creates new challenges for affordable access to new medicines around the world. Using insights from his research on price regulation, incentives for innovation, and universal health coverage in global bio-pharmaceutical markets, Chirantan Chatterjee will consider how the future may unravel for affordable access to new medicines in the Global North and South.

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Chatterjee 120822
Chirantan Chatterjee is an applied microeconomist and a Reader in the Economics of Innovation at the University of Sussex. He is also a Visiting Fellow at the Hoover Institution, Stanford University, and Visiting Faculty, IIM Ahmedabad, India. His research interests are in the economics of innovation, pharmaceutical economics, and global health. He has published in top peer-reviewed journals like Management Science, RAND Journal of Economics, Journal of Development Economics, Journal of Health Economics, Research Policy, Production and Operations Management, Journal of Business Ethics, Journal of Environmental Economics & Management and Social Science & Medicine among others. His new co-edited book on Covid-19 and Grand Challenges for Health, Innovation and Economy is forthcoming in 2023 with World Scientific. Chatterjee's research has in the past been supported by the NSF during his dissertation work at Carnegie Mellon University from where he obtained his PhD in 2011. His current research is supported by the Wellcome Trust India Alliance & Johns Hopkins Alliance for a Healthy World. Chatterjee has also consulted for the United Nations, World Bank, and the World Health Organization on Covid-19, Universal Health Coverage, and Incentives for Medical Innovation. View more on his personal website at www.chirantanchatterjee.com.

Jianan Yang

Via Zoom Webinar

Chirantan Chatterjee Reader in Economics of Innovation, Science Policy Research Unit, Business School, University of Sussex; Visiting Fellow Hoover Institution, Stanford University; Visiting Faculty, IIM Ahmedabad, India
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Incentives for health behaviors are an increasingly important policy tool in both developed and developing countries, and there is widespread interest in improving their effectiveness. However, different contracts are likely to be more effective for different people. Mechanism design offers two strategies to improve contract effectiveness—tagging on observables (i.e., 3rd-degree price discrimination), and offering a menu of contract choices (i.e., 2nd-degree price discrimination)—but a key concern with both is that participants with private information might self-select into contracts that are favorable to the agent but less effective from the perspective of the principal. We adapt each of these strategies to customize incentive contracts for walking. Using a randomized controlled trial among more than 5,000 adults in urban India, we show that both mechanisms increase physical activity, leading to a 75% increase in steps walked relative to the effect of a one-size-fits-all benchmark. Moreover, we find that the concern that participants will self-select into less effective contracts is not only misplaced, but exactly backwards. Instead, a common force in health behavior settings—commitment motives—leads agents to prefer more effective contracts under both mechanisms. In particular, sophisticated time-inconsistent agents demand contracts that commit their future selves to walk more, bringing their preferences in partial alignment with the principal and improving the effectiveness of customization.

 

Ariel Zucker 111722Ariel Zucker is an assistant professor in the Department of Economics at UC Santa Cruz. Her research studies policies to improve health and environmental conditions among underserved communities worldwide. Many of her projects focus on countering behavioral biases in personal decision making. Prior to arriving in Santa Cruz, Dr. Zucker did a postdoc at UC Berkeley ARE, and earned her Ph.D. in economics from MIT.

Jianan Yang

Via Zoom Webinar.

Ariel Zucker Assistant Professor of Economics, University of California Santa Cruz
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South Korea aspires to achieve the status of a global vaccine hub as a national strategic policy priority. South Korea’s biomanufacturing industry has ramped up the development and production of therapeutic treatments and vaccines to meet the public health demands of the pandemic. The government has responded by promoting public-private partnerships to expand vaccine production capacity to meet current and future needs domestically and abroad in LMICs. To bolster this strategy, the government has entered into partnerships with international organizations, namely the WHO, ADB, and IVI, by establishing training hub programs for a global biomanufacturing workforce in 2022.

This paper examines South Korea’s mechanisms and strategy towards becoming a vaccine hub, the origins of which predate the Covid-19 pandemic but were again spurred by vaccine nationalism and challenges to access early in the pandemic.

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Irene Kyoung
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Co-sponsored by Peking University and the Asia Health Policy Program

Time cost of healthcare is important but is largely overlooked in the literature. This paper investigates how time cost affects the healthcare usage in both China and the US. Using the retirement age policy in both countries, we first employ a Regression Discontinuity Design (RDD) and show that the hospitalization rate persistently increases by 20-30 percent just after retirement age. The effects are larger and more significant among the people with higher time costs prior to retirement. Then, we use the school starting date and provide further significant evidence of the impact of time cost on hospitalization among the age-eligible children. These results underline the remarkable impact of time cost on healthcare usage and provide a more comprehensive picture of moral hazard in health insurance.

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Wei Huang 102022
Dr HUANG Wei is an Associate Professor at the National School of Development (NSD), Peking University. Previously, he was an assistant professor at Emory University and National University of Singapore. He received his Ph.D. in economics from Harvard in 2016. His research fields include public economics, labor economics, and health economics. His research work has been published in journals such as Review of Economic and Statistics, American Economic Journal: Applied Economics, Nature, Journal of Economic Perspectives, Journal of Development Economics, Journal of Labor Economics, etc. He is a co-editor for Economics of Transition.

Jianan Yang

Via Zoom Webinar.

Wei Huang Associate Professor, the National School of Development (NSD), Peking University
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Asia Health Policy Postdoctoral Fellow, 2022-23
Jianan_Yang.jpg Ph.D.

Jianan Yang joined the Walter H. Shorenstein Asia-Pacific Research Center (Shorenstein APARC) as the 2022-2023 Developing Asia Health Policy Postdoctoral Fellow. She recently obtained her Ph.D. in Economics at the University of California San Diego. She holds B.A. in Economics and Mathematics from the Renmin University of China. Her research lies in the intersection of development and health economics and revolves around what drives the sub-optimal healthcare-seeking behaviors in developing countries and how they can be improved by leveraging price or non-price mechanisms.

Yang views health as a fundamental part of human development. People in developing countries usually face additional barriers to accessing healthcare resources because of underqualified providers on the one side, lower income levels, insufficient insurance coverages, and a lack of information on the other side. Because markets in healthcare settings are usually characterized by imperfect competition and government regulations, Yang thinks it is important to evaluate the policies’ impacts on various aspects of the healthcare system. Through understanding the underlying constraints, we can think about how the policy can be designed more efficiently.

Yang’s dissertation studied how patients’ chronic condition drug utilization responds to price reductions in China. By documenting a larger increase in utilization and a meaningful reduction in underuse among the uninsured, the study suggests that the price elasticities would be higher in developing countries and there will be larger welfare benefits from such price reductions resulting from squeezing out the price markups of the pharmaceutical companies due to market power. The finding suggests that cost is a barrier to both drug take-up and adherence, especially among the lower-income population who meanwhile are more likely to not have insurance coverage.

At APARC, Yang further accessed the underlying factors affecting people’s healthcare-seeking behaviors including the role of cost, information, and behavioral bias. She also extended her research agenda to the other sectors of the healthcare system. 

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As healthcare costs for patients with non-communicable diseases such as diabetes have risen, governments and healthcare providers have sought creative measures to align financial incentives with better patient outcomes. One incentive payment system known as “pay-for-performance” (P4P), in which providers are beholden to metric-driven outcomes, represents a potential path forward for healthcare providers to improve healthcare processes, resulting in higher quality and better patient health outcomes. The evidence on the effectiveness of P4P programs, however, is mixed.

To address this uncertainty, a new study, published in The European Journal of Healthcare Economics, assesses the effectiveness, in monetary terms, of a P4P program for patients with diabetes at a hospital system in Taiwan. 

The study coauthors, including APARC’s Asia Health Policy Program Director and FSI Senior Fellow Karen Eggleston, employed new patient-level data on clinical indicators, utilization, and expenditures, combined with data from the national death registry, to better understand the costs and benefits of the P4P program. Their results show that Taiwan’s implementation of the P4P program for diabetic care yielded positive results in terms of net value, defined as the value of life years gained minus the cost of care.


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Assessing Net Value of Taiwan’s P4P

Taiwan’s Bureau of National Health Insurance (now National Health Insurance Administration) introduced P4P in 2001 and enhanced the program in 2006 with an incentive for pay-for-reporting of outcomes. Financial incentives were used to encourage continuity of care with metrics such as new patient enrollment, follow-up visits, and annual reports, each tied to a specific monetary value. The program’s features are common across P4P, so the study’s findings have implications in other settings that incorporate similar designs in their P4P programs.

The study compares two different groups of patients at a large regional hospital in Taiwan, one consisting of newly enrolled P4P patients and another using P4P patients who have been enrolled since the beginning of the program. The researchers leverage detailed clinical data not used in previous assessments of the P4P program to better identify both costs and longer-term clinical outcomes based on measured biomarkers and predicted mortality.

Using an economic cost-benefit analysis conducted from a budgetary perspective, the study is the first analysis of any P4P program that estimates changes in the quality-adjusted price index relative to usual care. The authors consider health benefits in terms of survival and predicted survival and convert them into monetary terms. This net value approach is especially useful for policymakers and healthcare administrators who implement value-based purchasing and monitor outcomes for any service delivery innovation over time.

“These encouraging findings of the positive value of quality improvement net of expenditures adds evidence to the literature that has found mixed results of P4P programs.”

The study finds that Taiwan’s P4P program provided a positive net value for payers and patients, ranging from $40,084 USD to $348,717 USD. These positive net value results are primarily derived from health outcomes as measured by lower mortality rates in the P4P versus non-P4P cohorts, across both newly enrolled and continuously enrolled groups of patients. According to the authors, “these encouraging findings of the positive value of quality improvement net of expenditures adds evidence to the literature that has found mixed results of P4P programs.” 

 This study develops a new model for assessing the net value of service delivery innovations like P4P programs that can be applied in other contexts globally, providing healthcare systems researchers with new tools to better understand an emergent option for incentivized care. With a more economically-translatable understanding of P4P programs, this research helps build the bridge between the oft-disparate worlds of healthcare and policy.

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Education Level Will Widen Disparity in Health Outcomes of the Future Elderly Population, New Study Projects

In the first study to compare the progression of educational disparities in disability across two rapidly aging Asian societies, APARC coauthors Cynthia Chen and Karen Eggleston project that from 2015 to 2050, elders with high educational attainment will have a lower prevalence of functional disability and chronic conditions compared to elderly with low educational attainment.
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New Approaches to Aging: Understanding and Managing Society-Level Characteristics in Elderly Populations

Broadening the existing scholarship on aging and the needs of different societal groups, Cynthia Chen, Visiting Scholar at APARC’s Asia Health Policy Program, presents nuanced and comprehensive aging metrics that account for the critical factors that influence societal function.
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Japanese Population Projected to Live Longer Without Dementia

A new microsimulation projects that over the next 20 years, Japanese people will live longer without dementia, but older women with a less than high school education will benefit less than men.
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In the first study to evaluate pay-for-performance implementation at a hospital system in Taiwan, APARC’s Asia Health Policy Program Director Karen Eggleston and co-authors reveal how incentive-based measures to ensure continuity and quality of care resulted in positive health outcomes.

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Global Affiliate Visiting Scholar, 2022-23
Reliance Life Sciences
Jitukrushna Swain

Jitukrushna Swain is a global affiliate visiting scholar at the Walter H. Shorenstein Asia-Pacific Research Center (Shorenstein APARC) for 2022-23. Swain has over thirteen years of experience in business development, core scientific research and project management of pharmaceutical products and has been with Reliance Life Sciences Pvt. Ltd., India since 2015. Currently, he is designated as Senior Manager in the Corporate Development team. His current responsibilities include business development for international regulated market (including out-licensing deals for Finished Dose Formulations and client management); cross-functional coordination for product registration and market launch; portfolio management; sales and distribution network development for pharmaceutical products; and supporting the international clients by query response to techno-commercial requirements. Swain received his master's degree in bio-technology with specialization in industrial microbiology and fermentation technology from Sambualpur University, India in 2009.

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Pay-for-Performance (P4P) to better manage chronic conditions has yielded mixed results. A better understanding of the cost and benefit of P4P is needed to improve program assessment.

To this end, we assessed the effect of a P4P program using a quasi-experimental intervention and control design. Two different intervention groups were used, one consisting of newly enrolled P4P patients, and another using P4P patients who have been enrolled since the beginning of the study. Patient-level data on clinical indicators, utilization and expenditures, linked with national death registry, were collected for diabetic patients at a large regional hospital in Taiwan between 2007 and 2013. Net value, defined as the value of life years gained minus the cost of care, is calculated and compared for the intervention group of P4P patients with propensity score-matched non-P4P samples.

We found that Taiwan’s implementation of the P4P program for diabetic care yielded positive net values, ranging from $40,084 USD to $348,717 USD, with higher net values in the continuous enrollment model.

Our results suggest that the health benefits from P4P enrollment may require a sufficient time frame to manifest, so a net value approach incorporating future predicted mortality risks may be especially important for studying chronic disease management. Future research on the mechanisms by which the Taiwan P4P program helped improve outcomes could help translate our findings to other clinical contexts.

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Karen Eggleston
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Noa Ronkin
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The Walter H. Shorenstein Asia-Pacific Research Center (APARC) is pleased to invite applications for a suite of fellowships in contemporary Asia studies to begin fall quarter 2023.

The Center offers postdoctoral fellowships that promote multidisciplinary research on contemporary Japan and contemporary Asia broadly defined, inaugural postdoctoral fellowships and visiting scholar positions as part of the newly launched Stanford Next Asia Policy Lab, and a fellowship for experts on Southeast Asia. Learn more about each opportunity and its eligibility and specific application requirements:

Postdoctoral Fellowship on Contemporary Japan

Hosted by the Japan Program at APARC, the fellowship supports research on contemporary Japan in a broad range of disciplines including political science, economics, sociology, law, policy studies, and international relations. Appointments are for one year beginning in fall quarter 2023. The application deadline is December 1, 2022.
 

Shorenstein Postdoctoral Fellowship on Contemporary Asia

APARC offers two postdoctoral fellowship positions to junior scholars for research and writing on contemporary Asia. The primary research areas focus on political, economic, or social change in the Asia-Pacific region (including Northeast, Southeast, and South Asia), or international relations and international political economy in the region. Appointments are for one year beginning in fall quarter 2023. The application deadline is December 1, 2022.
 

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The Korean Wave, which has unique characteristics and continues to evolve in intriguing directions, could become a first mover on the global cultural scene.
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The Center offers a suite of fellowships for Asia researchers to begin fall quarter 2023. These include postdoctoral fellowships on contemporary Japan and the Asia-Pacific region, inaugural postdoctoral fellowships and visiting scholar positions with the newly launched Stanford Next Asia Policy Lab, and fellowships for experts on Southeast Asia.

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Michael Breger
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As populations age, societies must take into account the nuanced needs of different groups. This is the research domain of Cynthia Chen, who joined the Walter H. Shorenstein Asia-Pacific Research Center as visiting scholar with the Asia Health Policy Program during the 2022 winter and spring quarters. An Assistant Professor at the National University of Singapore (NUS), Chen’s current research focuses on the well-being of older adults, healthcare financing, and the economics of aging. 

Drawing on support from Singapore’s Ministry of Health, Ministry of Education, the U.S. National Institutes of Aging, and the Thai Health Promotion Foundation among others, Chen explores how demographic, economic and social changes affect the burden of care, financing needs, and optimal resource allocation in the future. 

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In a recent talk at APARC, Chen presented findings on gender and socioeconomic differences in aging, exploring the ways in which such society-level characteristics can have major positive and negative effects on the health and well-being of older persons. 

“We must move beyond the archaic old-age dependency ratios and metrics, such as GDP, which neglect many of the critical factors that influence societal function”
Cynthia Chen
Visiting Scholar, Asia Health Policy Program

According to Chen, these effects are interconnected with factors including access to effective health care, support systems that enhance function and restrict dependency, and programs assuring financial security and opportunities for older persons to effectively engage in society. “We must move beyond the archaic old-age dependency ratios and metrics, such as GDP, which neglect many of the critical factors that influence societal function,” Chen argued.

Finding Better Metrics for Aging

Gender and socioeconomic differences affect a country's ability to support its older adult population. Specifically, the longevity risk associated with females' longer life expectancy entails different needs between genders in old age. Chen aims to quantify gender differences in the aging experience of Organization for Economic Co-operation and Development (OECD) countries and compare differences in projections of disability and chronic diseases among future cohorts of older adults, including disparities by educational attainment.

In order to gain a more nuanced perspective on aging data, Chen drew data from The Aging Society Index, composed of established and available social and economic measures. The Index provides a quantitative estimate of the degree to which a society is successfully adapting to demographic transformation.

Much of Chen’s time is spent focusing on how to address gender-specific needs when developing policies and programs for aging societies. Chen cites The Network on an Aging Society, which defines a successfully aging society as “one which provides for the general well-being of older adults, is cohesive with minimal tension between generations and major subgroups, productive with opportunities for engagement both within and outside the workforce, and is equitable and secure.” Such society-level characteristics are necessary to understand the difference between successful and unsuccessful policies. 

Chen identifies systemic gender differences across critical domains of successful social aging that favor males. Thus, Chen argues, for many wealth or income-based measures, such as security, equity and productivity, males experience an advantage, which suggests room for improving women’s standing in paid work, job opportunities, and retirement income. One aspect where women do have an advantage is life expectancy. However, they tend to live longer in poorer health, reflected in a lower well-being score. 

Likewise, the gender disparity in cohesion is significantly driven by differences in co-residence rates, which is attributable to women outliving their spouses. These findings suggest that gender-specific needs should be considered when engineering policies and programs for aging societies. 

Varying Rates of Functional Disabilities 

Gender is not the only society-level characteristic that Chen investigates in her resarch on aging. In a recent study, published in Asian Development Review, Chen and her co-authors, including AHPP Director and FSI Senior Fellow Karen Eggleston, shed light on the dynamic evolution of the health and functional disparities of the future elderly.

“Despite overall increases in educational attainment, all elderly, including those with a college degree, experience an increased burden of functional disability and chronic diseases because of survival to older ages.”
Cynthia Chen
Visiting Scholar, Asia Health Policy Program

In order to understand the differences in aging and its relationship with functional disabilities across multiple societies, Chen looked at data from Korea and Singapore. While the two nations have a similar pace of aging, they differ in the rate of increase in functional disability and chronic diseases. This may be due to many factors, including diet, lifestyle, and cultural differences, Chen suggests. Most notably, older adults with high educational attainment are projected to have a lower prevalence of functional disability and chronic diseases, and consistent across gender in both Korea and Singapore. 

The study employs a new model to compare projections of functional status and disability among future cohorts of older adults, including disparities in disability prevalence by educational attainment. These changes will have important implications for social protection systems, including the financing and delivery of long-term care and health care. The study highlights potential differences in the aging experience by gender and education in each country to inform social and healthcare policy and provides a common platform for international comparison to identify and compare challenges across countries.

Studying aging and effective medical care in late adulthood, especially with an eye for society-level characteristics, is an urgent task. Chen’s research complements the existing literature on life-protection activities, further underscoring the importance of investment in healthy aging and control of chronic disease so that the future elderly may receive appropriate care.

Cynthia Chen

Cynthia Chen

Visiting Scholar, Asia Health Policy Program
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In the first study to compare the progression of educational disparities in disability across two rapidly aging Asian societies, APARC coauthors Cynthia Chen and Karen Eggleston project that from 2015 to 2050, elders with high educational attainment will have a lower prevalence of functional disability and chronic conditions compared to elderly with low educational attainment.
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Strengthening the Frontline: How Primary Health Care Improves Net Value in Chronic Disease Management

Empirical evidence by Karen Eggleston and colleagues suggests that better primary health care management of chronic disease in rural China can reduce spending while contributing to better health.
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Broadening the existing scholarship on aging and the needs of different societal groups, Cynthia Chen, Visiting Scholar at APARC’s Asia Health Policy Program, presents nuanced and comprehensive aging metrics that account for the critical factors that influence societal function.

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